The best way to Organize Full Genome Sequencing

Genomics is an area of technology that changes at an alarmingly rapid rate. It is difficult to locate samples of other fields which have undergone change at similar rates, but comparisons could are the evolution of computer technology in the last several decades or the rapid growth of Internet startups in the 90s. Unlike these examples, the growth of genome sequencing technology is restricted to a specific technological sector, or at the least, it’s been until now.

Sequencing technology is now passing a crucial point, where the cost of whole genome sequencing is actually below the cost of owning a conventional panel of genetic tests. Though it is difficult to calculate a precise figure with this, it probably is based on the number of $1K-$10K. Illumina’s HiSeq platform or IonTorrent’s Proton both promise genomic sequencing in this range, in addition to Complete Genomics. Even as we pass this time, genome sequencing moves from the realm of research technology to viable clinical diagnostic test.

The results of this change can be observed in the growing widespread curiosity about sequencing technology. While technologies in this area have revolutionized many regions of research in the last decade, their used in clinical settings has profound implications with this industry. Research applications can only just provide a restricted supply of profits. Moving into clinical applications provides access to a much bigger level of capital, both due to the larger market and higher profit margins.

The clinical introduction of genome sequencing technology will change many areas of healthcare within the next few years. Genome sequencing could eventually take the spot of a typical part of a patient’s healthcare record, in much the same way as blood type and allergies to medication are used today. However, we’ve a lot of ground to cover before we get to the point. For entrepreneurs in this 유전학  field, this equates to a selection of exciting opportunities.

While interpretation of genomic has been a significant part of research, the growing use of this data in clinical fields will create a great demand for the unambiguous interpretation of results. Physicians want an unambiguous questions such as for instance disease predisposition, and they’d like a reliable party to assume the responsibility for causeing the judgement. Recently, an increasing quantity of companies have entered the region of genomic data interpretation, many of them small startups such as for instance Genformatic, a Bioinformatics company located in Austin. Larger companies have also begun to concentrate on providing these services. As this industry evolves, it is likely that more companies may enter this realm, and it is likely to be interesting to observe how things develop in this area.

While a person with experience in Molecular Biology possesses the necessary skills to get ready and run libraries, a lot of things can fail in this process. Even in pure research applications, sample preparation is an increasingly common service given by a number of centers, in addition to boutique services, such as for instance Genome Organizer’s ChIP-Seq service. It’s not too researchers can’t perform these tasks, however when they’re readily available for a fee, they see little benefit to running these services for themselves. As genomic sequencing moves in to the clinical realm, demand for such services can be anticipated to increase. You can find few hospitals with the present capability to perform basic sample preparation, and this represents a brand new part of opportunity in this field.

One of many greatest regions of uncertainty in this area today is how samples are certain to get from physicians’ offices to sequencing centers, and who will inform patients of their results. Though medical school curricula may one day are the interpretation of genomic data, we’re far from that time today. Currently, even the administration and interpretation of Genetic tests is generally left to individuals in the field of Genetic Counseling, in collaboration with statisticians and specialists. Though it is likely that a selection of other professionals will take over the responsibility of this field in the future, it is likely that in the longer term, the growth will need place through this field.